| Primary Ingredient |
Purified salmon-derived polynucleotides (PDRN) |
Platelet-rich plasma from the patient's own blood |
Cell-derived extracellular vesicles containing signaling molecules |
Hyaluronic acid |
| How It Works |
Supports tissue repair and collagen signaling |
Delivers natural growth factors from platelets |
Delivers signaling molecules that support cellular communication and tissue repair |
Hydrates the skin by attracting and retaining moisture |
| Primary Benefits |
Skin repair, improved texture, hydration, and elasticity |
Collagen stimulation and skin healing |
Skin regeneration, repair support, and overall skin rejuvenation |
Deep hydration and improved skin smoothness |
| Collagen Support |
Indirect through cellular signaling |
Direct through platelet-derived growth factors |
Supports collagen production through cellular signaling |
Limited collagen stimulation |
| Best For |
Fine lines, acne scars, skin texture, and overall skin quality |
Skin rejuvenation, healing support, and collagen production |
Patients seeking regenerative skin treatments and overall rejuvenation |
Dry, dehydrated, or dull skin requiring enhanced hydration |
| Treatment Source |
Standardized purified formulation |
Patient's own blood |
Laboratory-prepared biologic product (varies by manufacturer) |
Commercially manufactured hyaluronic acid gel |
| Consistency |
Standardized between treatments |
Varies based on the patient's platelet concentration |
Standardized by manufacturer, depending on the product |
Standardized formulation |
| Typical Downtime |
24–72 hours |
24–72 hours |
24–72 hours |
Minimal to 24 hours |
| Common Use with Microneedling |
Frequently combined to support skin repair and rejuvenation |
Commonly combined to stimulate collagen production |
Often paired to support skin regeneration |
May be used after microneedling to improve hydration |
| Ideal Candidate |
Patients seeking long-term skin repair and healthier skin quality |
Patients looking for a natural treatment using their own growth factors |
Patients interested in regenerative skin therapies |
Patients primarily focused on improving skin hydration |