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The First Oral GLP-1 FDA-Approved for Weight Management

Many people fail to lose weight, not because of lack of effort. They fail because of constant hunger cravings and their body’s resistance to change. Prescription GLP-1 medications have helped solve this problem for many patients. But not everyone is comfortable with the idea of weekly injections.

With the Wegovy® pill, you may not need injections. It is the first oral GLP-1 receptor agonist approved in the U.S. for weight management. At Allure Esthetic in Seattle, we provide prescriptions for Wegovy® (semaglutide) tablets based on medical eligibility and detailed evaluation.

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What Is the Wegovy® Pill?

The Wegovy® pill is a prescription medication used for medical weight management. It is taken once daily orally, unlike most recognized GLP-1 weight-loss medications, which are injections. The medication contains semaglutide, which helps regulate appetite and fullness. Wegovy® tablets are FDA-approved for weight loss in eligible adults.

How the Wegovy® Pill Works for Weight Loss

GLP-1 is a natural hormone released after eating. It helps the body feel full and reduces hunger. Wegovy® works by activating GLP-1 receptors in the body. Wegovy® supports weight loss by:

  • Helping patients feel full faster during meals
  • Reducing hunger between meals
  • Supporting portion control
  • Decreasing frequent food cravings
  • Helping limit late-night or emotional eating
  • Making healthier food choices easier
  • Supporting consistent eating habits
  • Reducing overeating over time

Wegovy® is not a quick fix. It should be used alongside a healthy diet and regular exercise.

Who May Qualify for Wegovy® Pills in Seattle?

In general, adult weight-loss medication candidates often fall into one of these groups:

  • BMI ≥ 30 (obesity), or
  • BMI ≥ 27 (overweight) with a weight-related condition

A consultation is the safest way to confirm candidacy because it allows us to review:

  • Current medications (including diabetes medications)
  • Weight history and prior attempts for weight loss
  • Blood pressure, cholesterol, and other risk factors
  • Medical history and contraindications
  • Lifestyle factors, such as sleep, nutrition patterns, and activity level

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How to Take Wegovy® Tablets

Follow these instructions from the FDA to help the medication absorb properly:

  • Take Wegovy® tablets once daily on an empty stomach in the morning with water (up to 4 ounces).
  • Do not take the tablet with liquids other than water.
  • Swallow tablets whole. Do not split, crush, chew, or dissolve.
  • After taking the tablet, wait at least 30 minutes before eating food, drinking beverages, or taking other oral medications.

If you miss a dose of Wegovy® tablet, skip the missed dose. You can take the next dose the following day.

Wegovy® Pill Dosing Schedule

Wegovy® tablets follow a gradual dose-increase schedule to help the body adjust and to reduce the chance of stomach-related side effects. Each step allows time for tolerance to improve before moving to the next dose, and not every patient progresses at the exact same pace. For adults, the standard dosing plan is:

  • Days 1–30: 1.5 mg once daily
  • Days 31–60: 4 mg once daily
  • Days 61–90: 9 mg once daily
  • Day 91 and onward: 25 mg once daily (maintenance)

The tablet should be taken once per day exactly as prescribed. Don’t take more than one tablet in a single day. If side effects occur, you may be advised to stay on a lower dose longer before increasing to the next level.

How Much Weight Can Patients Lose on the Wegovy® Pill?

In clinical trials, adults who took Wegovy® pills once daily and followed the treatment plan lost an average of about 16–17% of their body weight. Individual results may vary, with outcomes depending on factors like:

  • Dose tolerance: Patients who tolerate dose increases well are more likely to stay on treatment long enough to see meaningful results.
  • Consistency: Taking the medication daily as prescribed plays a major role in achieving and maintaining weight loss.
  • Food choices: Healthier, balanced meals support better appetite control and more sustainable weight reduction.
  • Protein intake: Adequate protein helps preserve muscle mass and promotes fullness during weight loss.
  • Activity level: Regular physical activity enhances fat loss and helps maintain long-term results.
  • Sleep: Poor sleep can interfere with appetite hormones and slow weight loss progress.
  • Stress: High stress levels may increase cravings and make weight management more difficult.
  • Maintenance: Continuing treatment and lifestyle habits are important for keeping the weight off over time.

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Common Side Effects

GLP-1 medications often affect the stomach, especially when starting treatment or increasing the dose. With Wegovy®, some people may notice nausea, diarrhea, vomiting, constipation, stomach discomfort, headache, or fatigue. These effects usually lessen as the body adjusts. Your provider will adjust dosing when needed. You may also follow these simple steps to help reduce discomfort while your body adjusts:

  • Stay well hydrated
  • Eat smaller meals
  • Choose easy-to-digest foods
  • Avoid heavy or greasy meals
  • Increase fiber intake

Safety Considerations

Wegovy® is a prescription medication and should only be used under medical supervision. Before prescribing, we will review your medical history to make sure this option is appropriate.

  • Thyroid conditions: Wegovy® should not be used if there is a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
  • Pregnancy and breastfeeding: Wegovy® should not be used during pregnancy or while breastfeeding, as it may cause harm to an unborn baby.
  • Pancreatitis risk: Severe or ongoing stomach pain, especially pain that spreads to the back or comes with vomiting, should be evaluated right away.
  • Gallbladder issues: Rapid weight loss and GLP-1 medications may increase the risk of gallstones in some patients.
  • Medication interactions: Wegovy® can slow digestion, which may affect how other oral medications are absorbed.
  • Surgery and anesthesia: Always tell healthcare providers if you are using Wegovy® before any planned procedures.

Our team will explain these considerations in detail and continue to monitor your response to treatment to help ensure ongoing safety.

Wegovy® Pill at Allure Esthetic

Starting Wegovy® pills begins with a medical consultation to ensure this treatment is safe, appropriate, and aligned with your weight-loss goals. At Allure Esthetic, we offer free in-person and virtual Wegovy® consultations for patients. Your consultation includes:

  • A complimentary medical evaluation
  • Personalized diet and exercise guidance to support healthy, sustainable weight loss
  • Monthly follow-up appointments to monitor progress, adjust dosing if needed, and manage side effects

This structured approach allows us to prescribe Wegovy® pills responsibly. We are here to provide ongoing support to help patients stay consistent.

Frequently
Asked Questions

1. Is the Wegovy® pill FDA-approved for weight loss?

Yes. Novo Nordisk announced FDA approval of Wegovy® pill (once-daily oral semaglutide 25 mg) for weight management in the U.S.

Is the Wegovy® pill the same as the Wegovy® injection?

Both the Wegovy pill and the Wegovy® injection contain the same active ingredient, semaglutide, but the delivery is different.

How do Wegovy® tablets need to be taken?

Wegovy® tablets need to be taken once daily on an empty stomach in the morning with up to 4 ounces of water only. They should be swallowed whole, then wait at least 30 minutes before food, beverages, or other oral medications.

What if a dose is missed?

If a Wegovy® tablet dose is missed, skip it and take the next dose the following day.

What are the most common side effects of Wegovy® pills?

Common side effects of Wegovy® pills can include nausea, diarrhea, vomiting, constipation, abdominal pain, headache, and fatigue.

Who should not take Wegovy®?

Wegovy® is not recommended for patients with a personal or family history of medullary thyroid carcinoma (MTC) or MEN 2.

Can Wegovy® be used during pregnancy?

The FDA label states Wegovy® may cause fetal harm and should be discontinued when pregnancy is recognized for weight reduction or cardiovascular risk reduction. It also advises stopping at least 2 months before a planned pregnancy due to the long half-life.

Is the Wegovy® pill approved for teens?

No. The safety and effectiveness of Wegovy® tablets have not been established in pediatric patients.

Is Wegovy® available as a pill?

Yes, Wegovy® is FDA-approved as a once-daily oral tablet for weight management in eligible adults.

How much does the Wegovy® pill cost?

The cost of Wegovy® pills varies based on insurance coverage, pharmacy pricing, and available savings programs. Exact pricing is confirmed after consultation.

Is Wegovy® going to be in pill form soon?

Wegovy® is already approved and available in pill form following FDA authorization for oral semaglutide.

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